Sporadic cerebellar ataxia associated with gluten sensitivity
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چکیده
منابع مشابه
Sporadic cerebellar ataxia associated with gluten sensitivity.
A total of 104 patients with sporadic cerebellar ataxia were tested for antigliadin and antiendomysium antibodies. Twelve individuals (11.5%) with gluten sensitivity underwent duodenal biopsy and extensive clinical, electrophysiological, neuropsychological, radiological and laboratory investigations including human leucocyte antigen (HLA) typing. Two patients showed typical changes of gluten-se...
متن کاملGluten sensitivity: associated sporadic cerebellar ataxia in Taiwan.
PURPOSE Gluten sensitivity (GS) is related to the pathogenesis of sporadic or hereditary ataxia. METHODS Total of 194 healthy controls and patients with either hereditary ataxia (n=207) or sporadic ataxia (n=361) were tested for the circulating gluten-related autoantibodies which serve as biomarkers to interpret the existence of GS. RESULTS The incidences of GS in each population were 1% in...
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Gluten sensitivity can manifest with ataxia. The metabolic status of the cerebellum was investigated in 15 patients with gluten ataxia and 10 controls using proton MR spectroscopy. Significant differences were present in mean N-acetyl aspartate levels at short echo time and N-acetyl aspartate/choline ratios at long echo time between the patient and control groups. These data support the hypothe...
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The term acute cerebellar ataxia is used to designate a syndrome of uncertain etiology, occuring usually in young children and characterized by a relatively sudden onset of cerebellar signs (ataxia, intention tremor, and often nystagmus) which reach maximum intensity within a few days and then subside.'` In many of the reported cases an absence of prodromal symptoms, fever, nuchal rigidity, or ...
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1. The cerebellum has long been known to participate in movement control. One of the enduring theories of cerebellar function is that it "tunes" and coordinates sensorimotor traffic in other parts of the CNS. In particular, it has been implicated in the control of the sensitivity of muscle spindle stretch receptors through the fusimotor system. 2. The stretch sensitivity of spindle primary endi...
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ژورنال
عنوان ژورنال: Brain
سال: 2001
ISSN: 1460-2156
DOI: 10.1093/brain/124.5.1013